Complete the indicated task to unlock the corresponding character.
| Effect | How to unlock |
| Lou | Successfully complete the game to purchase Lou for $15,000. Lou comes with his skeleton guitar and two costumes (original devil outfit and werewolf viking).
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| Slash | Defeat him in the Boss battle in Career mode to unlock him for purchase at the store for $10,000.
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| Tom Morello | Defeat him in the Boss battle in Career mode to unlock him for purchase at the store for $10,000.
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