Search the indicated locations to find the corresponding Zodiac Chamber. Take its treasure to unlock the corresponding weapon or power.
Aquarius Blade: In Chapter 23, reach the first grind rail that you have to jump and take it back in the opposite direction. Ride it to the Chamber.
Aries Armor (Power): In Chapter 18, at the Hot Spring area with the Souflee, go to the left.
Cancer Claws: In Chapter 8, In the constellation storage room after defeating the Snong, do not take the Jump Pad. Instead, take the dead end path to the right and jump down.
Capricorn Club: In Chapter 20, when you get to the area that needs a key, go inside and take a right. Open the jail cell in the rear left and pass through the hidden wall.
Gemini Orbitars: In Chapter 6, defeat Dark Pit in the underground temple, then check the temple's corners.
Leo Cannon: In Chapter 10, sink the pedestal into the lava or jump over it. Enter into the next room and follow the left wall.
Libra Sponge (Power): In Chapter 14, reach the Boss door, then move in the opposite direction to find an electric door. Get up close to the door and dodge through it.
Pisces Heal (Power): In Chapter 24, take your first elevator to begin the trials, then go down the other flight of stairs.
Sagittarius Bow: In Chapter 2, go down the ramp (just before you meet Magnus), run through the tapestry hanging in one of the bends.
Scorpio Staff: In Chapter 16, get the Aether Ring and float down an opening. Look for an opening while floating and shoot the switch inside. You can now enter.
Taurus Arm: In Chapter 4, drop down to the Clubberskull pit from the room with the narrow path and two scythes. Jump into the glowing hole.
Virgo Palm: In Chapter 12, find the area that has an elevator after killing some monsters. Look towards it and a second elevator will be behind you. Take that elevator.