Complete the indicated task to unlock the corresponding character.
| Character | How to unlock |
| Deadpool | Complete the Washington D.C. level.
|
| Green Goblin | Defeat Green Goblin and Venom at the end of Wakanda Act 3.
|
| Hulk | Collect all five Gamma Regulators.
|
| Iron Fist | Choose the Rebel side.
|
| Jean Grey | Collect all five M'Kraan Shards.
|
| Ms. Marvel | complete the New York City level.
|
| Nick Fury | Complete the game.
|
| Songbird | Choose the Register side.
|
| Thor | Collect all five Asgardian Runes.
|
| Venom | Defeat Green Goblin and Venom at the end of Wakanda Act 3.
|
