When playing in Horde mode, go to the Day One map. Inside the Game room there should be a shield. Pick up the shield and go to one of the two staircases. Depending on which staircase you choose, you can select between a cycle of Longshot/Torque Bow or Mulcher/Mortar. Plant the shield in the middle of the staircase with the shield facing toward the bottom of the staircase. If placed properly, this will block larger enemies like the Bloodmounts and Boomers from reaching you, allowing for easy kills. There is plenty of cover for you to snipe drones running around and ducking for cover on the ground. It is best to kill a Mauler with a shield to plant additional shields. Drones and Sires will kick the shield down if you do not kill them as they run up. Even if they do, just run up the stairs and jump over the cover. You can kill anyone using blind fire or shooting and ducking. You can even plant a frag or smoke grenade somewhere for a quick kill or get some chainsaw action while they are down. Then, just set up your shields again and continue. Keep in mind when you kill the last enemy and the new horde begins, you have about twenty seconds before your shields will disappear. You must kick them down and replant them. You can also pick one up before you kill the last enemy.
When playing in Horde mode, go to the Blood Drive map. You should begin somewhere on top of a double staircase. One direction leads all the way down, while the other leads off to the side through a room then leading to a smaller staircase. Run to the room. There should be ether frags or an ink grenade behind the pillar (they cycle with each Horde). If it is ink, just die. Its easiest to start with frag grenades. Plant a grenade on each wall next to each staircase. Go back to the room and collect the grenades as they respawn. Stay outside one side of the room killing enemies. If someone runs up they will blow up; just replant the grenade when that happens. Also, you will hear the grenades explode if someone tries to sneak behind you. Once again, replant the grenade if this happens. This works best in Co-op mode because each player can only plant two grenades of the same type, and of course you can watch out for each other. If player one plants a smoke then plants a frag grenade, player one's smoke grenade will automatically explode. Using two people you can plant four frag or ink grenades. As you kill enemies, if someone gets too tough, just Roadie Run past a grenade. They will always chase you. When you get to Horde 3 you should have a Boomshield Mauler come for you. Kill him and take his shield. Plant the shield in one of the doorways where the grenades are located (two Maulers, two shields, two blocked doorways). With both players in the room, the grenades, and blocked doorways, fighting off enemies should not be as difficult. Before you kill the last enemy, load up on ammunition. You can get some ammunition back as each Horde begins. Remember to pick up your shields or replant them as the new Horde begins so that they do not disappear. The Torque Bow takes out most enemies fairly quickly with a headshot if you wind it until it self releases. If you run out of ammunition, you can melee behind the shield (the Torque Bow is the most powerful melee weapon) or tag with grenades. The flame thrower kills groups very fast.
This trick works better with only two players. In the "River" map, go any of the two houses with the sniper or torque bow. Put a grenade at the entrance then hide behind the columns there. Crouch for maximum cover, then wait for a Boomer with the shield to get in. Kill him and take his shield. Put it in the ramp so that no enemy can get in, then shoot away.