| Trophy | How to unlock
|
|---|
| Artery Medal (Bronze) | Gather 60 Golden medals in Veins Campaign mode.
|
| Brain Folds Master (Silver) | Score 5000 kills in Brain Wars Immune Badass Survival mode.
|
| Digest Warlord (Silver) | Complete all the Intestine Assault missions on Immune Badass difficulty.
|
| Gold Farmer (Bronze) | Gather 60 Golden medals in Brain Wars mode.
|
| Immune God (Silver) | Complete all Veins Campaign missions on Immune Badass difficulty.
|
| Intestine Hard Day (Silver) | Score 5000 kills in Intestine Assault Immune Badass Survival mode.
|
| Large Intestine (Bronze) | Gather 60 Golden medals in Intestine Assault mode.
|
| Meticulous (Bronze) | Read all Help Guides and the Credits section.
|
| Neurotic Lord (Gold) | Complete all the Brain Wars missions on Immune Badass difficulty.
|
| No Help Needed (Bronze) | Destroy 500 powerups of any kind.
|
| Pulse Master (Bronze) | Score 5000 kills in Veins Campaign Immune Badass Survival mode.
|
