| Trophy | How to unlock
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| A Day in the Life (Silver) | Play a game of MLB Today.
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| A Job Well Done (Platinum) | Unlock all Trophies.
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| A Pitcher's Best Friend (Bronze) | Turn a double play on Pro or higher, in a non-simulated game.
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| A Virtue (Bronze) | Face 10 pitches as the batter on Pro or higher in a non-simulated game.
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| A Whole New You (Bronze) | Choose a signature batting stance or pitching delivery in My Player or Create Player.
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| Booked a Ticket (Silver) | Clinch a Postseason Berth in Franchise Mode (play at least 20 games).
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| Count It (Bronze) | Complete and win a ranked match.
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| Domination (Bronze) | Strikeout 200 batters with your profile.
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| Don't Call It a Comeback (Bronze) | Win after being down by 4 after the 6th inning on Pro or higher, in a non-simulated game.
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| Down But Not Out (Bronze) | Get a hit with 2 strikes on Pro or higher, in a non-simulated game.
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| Grab Some Pine (Bronze) | Get a strikeout to end the inning on Pro or higher, in a non-simulated game.
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| High Crimes (Bronze) | Rob a Home Run on Pro or higher, in a non-simulated game.
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| Hurlers (Bronze) | Unlock 20 pitcher cards.
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| I Came, I Saw... (Bronze) | Hit a Walk-off Home Run on Pro or higher, in a non-simulated game.
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| It's Never Too Late (Bronze) | Get a 2-out RBI Hit on Pro or higher, in a non-simulated game.
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| Keep on Truckin' (Bronze) | Truck the Catcher and score on Pro or higher, in a non-simulated game.
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| King of the Hill (Bronze) | Get to the top of the Best of the Best ladder in Home Run Derby Mode.
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| Learning the Ropes (Bronze) | Achieve gold in all the drills.
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| Mid-Summer Classic (Silver) | Play the All-Star game in MLB Today.
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| My Fellow Man (Bronze) | Complete and win an online league game.
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| One Man Show (Bronze) | Throw a Perfect Game or a No-Hitter on Pro or higher in a 9 inning game, in a non-simulated game.
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| One and O (Silver) | Play and win opening day in Franchise Mode.
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| Production (Gold) | Drive in 250 RBI with your profile.
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| Remember Me (Silver) | Break a record in Franchise Mode (play at least 20 games).
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| Run the Risk (Bronze) | Steal a base after the 6th inning tied or down by 1 run on Pro or higher, in a non-simulated game.
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| State Farm - The Road to Victory (Bronze) | Get 3 consecutive batters on base on Pro or higher, in a non-simulated game.
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| Still Kicking (Bronze) | Strike out a batter with a pitcher who has low composure on Pro or higher, in a non-simulated game.
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| Stooges (Bronze) | Strikeout all three hitters in the inning on Pro or higher, in a non-simulated game.
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| Swingers (Bronze) | Unlock 25 hitter cards.
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| The Call (Silver) | Get called up to the Majors in My Player Mode.
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| The Goal (Silver) | Accomplish a Team Season Goal in My Player Mode.
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| The Hall (Silver) | Make the Hall of Fame in My Player Mode.
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| The Road to Greatness (Bronze) | Complete and win 3 ranked matches in a row.
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| The Spice of Life (Bronze) | Complete 10 online matches using 10 different teams.
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| The Star (Silver) | Make the All-Star team in My Player mode.
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| The Start (Silver) | Get your player's overall rating to 65 in My Player Mode.
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| The Team to Beat (Bronze) | Beat the New York Yankees in a completed online match.
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| The Top (Silver) | Become the #1 ranked player in your My Player organization.
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| The Truth (Silver) | Get your player's overall rating to 85 in My Player Mode.
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| This is Why I'm Here (Bronze) | Be successful in a major-league clutch moment in My Player Mode.
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| Thou Shall Not (Bronze) | Throw out a runner stealing a base on Pro or higher, in a non-simulated game.
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| Time to Run for Mayor (Bronze) | Hit 3 Home Runs in a single game with the same player on Pro or higher, in a non-simulated game.
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| To the Rescue (Bronze) | Bring in a pitcher, get a save with the tying run on base on Pro or higher, in a non-simulated game.
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| Trifectas Maximus (Bronze) | Throw a MAX pitch 3 consecutive times with Total Control on Pro or higher, in a non-simulated game.
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| What's Your Ring Size? (Silver) | Win a World Series in Franchise Mode (play at least 20 games).
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