Tapping a question mark next to a mission will show you its location. Tap the spot on the map and a little arrow will guide you towards it.
Manholes serve as fast travel spot, but they need to be open on both sides. Make sure you do it every time you come across one.
Some shops are only day/night specific. This means that you can only visit them at those times.
Purple stars on the map signify missions that you need to collect in order to start, so be on the lookout for them.
If you come across various foods like waffles and hot dogs, try to memorize where they are. You will need that information later on.
Find Santa Claus at night in the Shady district (he’s probably not delivering any presents there). If you fight him and win you will get 400 gold and a Santa figure.
You can turn on the little heart icon on one of your figures to make it your favorite and easier to find.
Always have a character that can do cleanse. It removes all the negative effects on your team. (Like in real life) buy stuff when it is on sale. You will save up a lot.