The best young team for a franchise is as follows.
SP: Fransisco Liriano (L), Minnesota
SP: Matt Garza (R), Tampa Bay
SP: Cole Halmes (L), Philles
SP: Felix Hernandez (R), Seattle
SP: Zach Duke (L), Pittsburgh
CP: Brad Zigler (R), Oakland
C: Joe Mauer (L/R), Minnesota
1B: Miguel Cabera (R/R), Detroit
2B: Dustin Pedroia (R/R), Boston
3B: David Wright (R/R), NY Mets
SS: Jose Reyes (S/R), NY Mets
LF: Grady Sizemore (L/L), Clevland
CF: Jacoby Ellsburry (L/L), Boston
RF: Nick Markakis (L/L), Baltimore
DH: Evan Longoria (R/R), Tampa Bay
Try the following team.
SP: Johan Santana
SP: CC Sabathia
SP: Cloe Hamels
SP: John Lacky
SP: Josh Bekkett
RP: Chad Bradford
RP: Ryan Madson
RP: JC Romero
CP: Brad Lidge
C: Joe Mauer
1B: Ryan Howard
2B: Chase Utley
3B: Evan Longoria
SS: Jimmy Rollins
OF: Manny Ramirez, Shane Victorino, Adam Dunn
DH: David Ortiz
J: Rod
Try the following team.
SP: Tim Lincecum
SP: C.C. Sabathia
SP: Joba Chamberlain
SP: Johan Santana
SP: Pedro Martinez
CP: Mariano Rivera
C: Jorge Posada
1B: Albert Pujols
2B: Brian Roberts
SS: Derek Jeter or Jose Reyes
3B: Alex Rodriguez
OF: Nick Swisher, Johnny Damon, Ichiro
DH: David Ortiz
For an unbeatable team in Season mode, choose the Detroit Tigers and turn "Force Trades" on. Perform the following trades. Although it does not always work, it is possible to get a 162-0 record if all the games are played well.
Jeremy Bonderman (SP) For Johan Santana (SP, NYY)
Edgar Renteria (SS) For Derek Jeter (SS, NYY)
Brandon Inge (3B) For Alex Rodriguez (3B, NYY)
Create one SP and one 1B and set the Attribute Points all the way up. Drop Carlos Guillen for the 1B. Drop Kenny Rogers for the SP.