Use the following steps when in the lab and cannot get the prisms. Next to the giant laser is a tall box that is big enough for you to fit inside. Jump up on top of it. There is a pole directly above it. Climb onto the pole, then go all the way over to the elevated part (with computers and and other objects). Jump down. There is a computer by itself in the corner. Hack it. The gun turret will then turn off. Run down the stairs and get the prisms. Someone will start coming towards the lab. Run over to the laser and put the prisms into it. Then, run over to the tall box and get inside. The door will shut. Stay in there until it is safe to exit (after the enemies are inside the lab). Jump out of the box and defeat the two men. Then, save Agent Jacobs. Use the laser to blow up the things on the wall near the tin shutter object. Note: There is one outside and another inside. Then put the toxic material into the fuel cell and exit.